This presentation will address the different interventions and actions currently available in the field of substance use among sexually- and gender-diverse individuals. It will also reflect upon potential future actions and the strategies to achieve them. Participatory approaches, both in research and in intervention, the inclusion of peers, as well as activism activities are interesting strategies to open up possibilities in this field. Working together and raising awareness among decision-makers of the issues surrounding substance use among sexually- and gender-diverse individuals are essential. This presentation will also provide an opportunity to discuss ways to influence public policy in the area of substance use and to include sexual and gender diversity in the priority populations for these policies.