For people living with HIV, current guidance doesn’t indicate additional measures necessary to prevent mpox infection. However, all people who are immunocompromised—including those living with HIV who are not receiving regular antiretroviral treatment or have a CD4 below 200—may have a higher likelihood of severe illness if they are exposed to the mpox virus. The vaccine currently offered in Canada (Imvamune) is shown to be safe for people living with HIV.
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