HIV pre-exposure prophylaxis (PrEP) was approved by Health Canada in February 2016, and a priority group for PrEP implementation is Indigenous Two-Spirit, gay, bisexual, trans, queer men and non-binary people (2S/GBTQ). We sought to examine population-level trends and demographic correlates of PrEPknowledge, interest and use among 2S/GBTQ in Canada.
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